Protecting children, families, and communities against influenza.

Flu and Sepsis

How are flu and sepsis related?

Sepsis is the body’s extreme reaction to any type of infection. The flu, which is a viral infection, can cause secondary complications such as sepsis. 

Flu and Sepsis

After four days in ICU, sepsis invaded her body and Kendra’s condition worsened.

Read Kendra's Story

What is Sepsis?

Sepsis is the body’s reaction to an uncontrolled infection, which can be bacterial, viral, or fungal in nature. These infections can cause a chain reaction in your body, causing tissue damage, organ failure, and even death. It is critically important to seek immediate medical attention if sepsis is suspected.

Who is at risk for developing sepsis as a secondary complication of flu?

ANYONE, regardless of health status, can fall victim to sepsis. People with chronic conditions, such as diabetes or lung disease, older adults, and young children are especially vulnerable to developing sepsis. 

Flu and Sepsis

Joseph suffered a catastrophic intestinal rupture as a result of H1N1 influenza that caused him to go into shock.

Read Joseph's Story

Symptoms of Sepsis

Flu and sepsis

Confusion or disorientation

Flu and sepsis

Shortness of breath

Flu and sepsis

Rapid heart rate

Flu and sepsis


Flu and sepsis

Shivering or feeling very cold

Flu and sepsis

Extreme pain or discomfort

Flu and sepsis

Clammy or sweaty 

How is sepsis diagnosed and treated?

Doctors use a number of physical findings to diagnose suspected sepsis, including fever, low blood pressure, increased heart rate, and difficulty breathing. Lab tests may also be used to check for signs of infection or organ damage.

Treatment for sepsis may include the use of antibiotics, oxygen, IV fluids, assisted breathing measures, and/or surgery to remove damaged tissue. 

More than 1.5 million people in the U.S. get sepsis every year.

hospitalization and death from flu and sepsis

Approximately 250,000 Americans die of sepsis every year. 

Sepsis complication in up to 30% of flu-related pediatric deaths

Did you know?

Sepsis is listed as a complication in up to

30% of pediatric flu-related deaths.

Influenza and sepsis

It wasn’t until after Trevor’s death that his physician father realized that his son’s flu infection had led to sepsis.

Read Trevor's Story

The Difference Between Sepsis and Septic Shock

Sepsis can progress to septic shock, which is a life-threatening condition. Septic shock is generally identified by a dramatic drop in blood pressure.

Influenza and Sepsis

Caroline's month-long battle with flu included secondary complications such as pneumonia, severe sepsis, septic shock, and hypoxemia.

Read Caroline's Story

Influenza and Sepsis

Less than 10 hours after arriving at the ER, Ayzlee passed away from septic shock, secondary to influenza.

Read Ayzlee's Story

Influenza and Sepsis

Despite Maya's lowered fever, she wasn't getting better, and in fact, seemed worse - a sign she was going into septic shock.

Read Maya's Story

Influenza and Sepsis

Amiah lost her life just 12 hours after her flu illness led to pneumonia and sepsis.

Read Amiah's Story

Where can I learn more about sepsis?

Stay Informed
Sign up for our Weekly Flu News and quarterly newsletter, Fighting Influenza, to stay up-to-date on the latest flu news.